Antitumor Effects of Systemic DNAse I and Proteases in an In Vivo Model

Conclusion. This study demonstrated that systemic treatment with DNAse I and a protease mix in rats decreases DNA and proteins from serum and that this treatment has antitumor effects. Our results support the hypothesis that circulating DNA could have a role in tumor progression, which can be offset by depleting it. Further studies are needed to prove this concept.

http://ict.sagepub.com/cgi/content/abstract/15/4/NP35?rss=1

Source: Integrative Cancer Therapies - November 16, 2016 Category: Cancer & Oncology Authors: Trejo-Becerril, C., Perez-Cardenas, E., Gutierrez-Diaz, B., De La Cruz-Sigüenza, D., Taja-Chayeb, L., Gonzalez-Ballesteros, M., Garcia-Lopez, P., Chanona, J., Duenas-Gonzalez, A. Tags: E-Only Section Source Type: research