Biodistribution and Clearance of Human Mesenchymal Stem Cells by Quantitative Three-Dimensional Cryo-Imaging After Intravenous Infusion in a Rat Lung Injury Model

This article demonstrates, for the first time, the use of three-dimensional cryo-imaging for single-cell quantitative tracking of intravenous infused clinical-grade mesenchymal stem cells in a clinically relevant model of lung injury. The important information learned in this study will help guide future clinical and translational stem cell therapies for lung injuries.

Source: Stem Cells Translational Medicine - November 16, 2016 Category: Stem Cells Authors: Schmuck, E. G., Koch, J. M., Centanni, J. M., Hacker, T. A., Braun, R. K., Eldridge, M., Hei, D. J., Hematti, P., Raval, A. N. Tags: Mesenchymal Stem Cells, Enabling Technologies for Cell-Based Clinical Translation Source Type: research