Neurodegenerative disease: Resisting the chop

Nature Reviews Neuroscience 17, 739 (2016). doi:10.1038/nrn.2016.153 Author: Sian Lewis It is currently unclear which forms of the protein tau contribute to Alzheimer disease (AD) pathology, but Δtau314, which is produced following caspase 2-mediated tau cleavage, is elevated in the brains of cognitively impaired mice and humans with AD. Here, in vitro expression of
Source: Nature Reviews Neuroscience - Category: Neuroscience Authors: Tags: Research Highlight Source Type: research