Rifampicin and isoniazid plasma concentrations in relation to adverse reactions in tuberculosis patients: a retrospective analysis

Conclusions:
High INH concentrations were common in patients with and without ADRs whereas RMP concentrations were low or within the normal range in most patients. Further studies are required to assess the association between high INH concentrations and the occurrence of ADRs.

Source: Therapeutic Advances in Drug Safety - November 14, 2016 Category: Drugs & Pharmacology Authors: Aït Moussa, L., El Bouazzi, O., Serragui, S., Soussi Tanani, D., Soulaymani, A., Soulaymani, R. Tags: Original Research Source Type: research