MicroRNA-125b Prevents Cardiac Dysfunction in Polymicrobial Sepsis by Targeting TRAF6-Mediated Nuclear Factor {kappa}B Activation and p53-Mediated Apoptotic Signaling

Conclusions. Increased myocardial miR-125b expression attenuates sepsis-induced cardiac dysfunction and improves survival. miR-125b may be a target for septic cardiomyopathy.

Source: The Journal of Infectious Diseases - November 13, 2016 Category: Infectious Diseases Authors: Ma, H., Wang, X., Ha, T., Gao, M., Liu, L., Wang, R., Yu, K., Kalbfleisch, J. H., Kao, R. L., Williams, D. L., Li, C. Tags: BACTERIA Source Type: research