Protease Inhibitor Resistance Remains Even After Mutant Strains Become Undetectable by Deep Sequencing

Conclusions. The virological response to daclatasvir plus asunaprevir treatment was low in patients with simeprevir treatment failure. PI resistance remains even after disappearance of mutant strains by deep sequencing.

Source: The Journal of Infectious Diseases - November 13, 2016 Category: Infectious Diseases Authors: Kan, H., Imamura, M., Uchida, T., Hiraga, N., Hayes, C. N., Tsuge, M., Abe, H., Aikata, H., Makokha, G. N., Chowdhury, S., Miki, D., Ochi, H., Ishida, Y., Tateno, C., Chayama, K. Tags: HIV/AIDS Source Type: research