Impaired Recognition of Mycobacterium tuberculosis by Alveolar Macrophages From Diabetic Mice

Conclusions. Reduced MARCO and CD14 expression contributes to defective sentinel function of alveolar macrophages, promoting tuberculosis susceptibility in diabetic hosts at a critical early step in the immune response to aerosol infection.

Source: The Journal of Infectious Diseases - November 13, 2016 Category: Infectious Diseases Authors: Martinez, N., Ketheesan, N., West, K., Vallerskog, T., Kornfeld, H. Tags: PATHOGENESIS AND HOST RESPONSE Source Type: research