Clinical outcomes of fungating breast cancer treated with palliative radiotherapy

ConclusionRadiotherapy is effective palliative treatment for patients with fungating breast cancer. High response rates of up to 90  % can be expected, with a median local progression-free survival of 10 months. With the advent of dose escalation techniques such as intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT), it is now technically possible to deliver high radiation doses to patients with low toxicity and risk to the adjacent normal organs. Nevertheless, whether higher doses or longer courses of radiotherapy confer better local control is a potential subject for further study.
Source: Journal of Radiation Oncology - Category: Cancer & Oncology Source Type: research