Reduced epicardial vagal nerve density and impaired vagal control in a rat myocardial infarction –heart failure model

Autonomic remodeling, characterized by sympathetic activation and vagal withdrawal, contributes to heart failure (HF) progression. However, the exact mechanism(s) responsible for vagal withdrawal in HF remain(s) unclear, and whether HF causes epicardial autonomic nerve remodeling is unknown.

Source: Cardiovascular Pathology - October 22, 2016 Category: Cardiology Authors: Matthew S. Delfiner, John Siano, Ying Li, Eduard I. Dedkov, Youhua Zhang Tags: Original Article Source Type: research