Transmission of Drug-Resistant Leprosy in Guinea-Conakry Detected Using Molecular Epidemiological Approaches

Molecular drug susceptibility testing was performed on skin biopsies from 24 leprosy patients from Guinea-Conakry for the first time. We identified primary drug resistance in 4 cases and a dapsone-resistant cluster caused by the same strain. Primary transmission of drug-resistant Mycobacterium leprae, including a rifampicin-resistant strain, is reported.

Source: Clinical Infectious Diseases - November 11, 2016 Category: Infectious Diseases Authors: Avanzi, C., Busso, P., Benjak, A., Loiseau, C., Fomba, A., Doumbia, G., Camara, I., Lamou, A., Sock, G., Drame, T., Kodio, M., Sakho, F., Sow, S. O., Cole, S. T., Johnson, R. C. Tags: BRIEF REPORTS Source Type: research