Efficacy and Safety of Two Dosages of Canrenone as Add ‐On Therapy in Hypertensive Patients Taking Ace‐Inhibitors or Angiotensin II Receptor Blockers and Hydrochlorothiazide at Maximum Dosage in a Randomized Clinical Trial: The ESCAPE‐IT Trial

ConclusionBoth canrenone dosages gave a decrease of blood pressure, with a better effect with the higher dose, with only a slight increase of potassium and creatinine levels, which were not clinically relevant.This article is protected by copyright. All rights reserved.

Source: Cardiovascular Therapeutics - November 12, 2016 Category: Cardiology Authors: Giuseppe Derosa, Pamela Maffioli, Maria D'Avino, Carla Sala, Amedeo Mugellini, Vito Vulpis, Salvatore Felis, Luigina Guasti, Riccardo Sarzani, Alessandro Bestetti, Massimo Vanasia, Giovanni Gaudio, Tags: EXPEDITED ($1500) Source Type: research