In vitro effects of water-pipe smoke condensate on the endocytic activity of Type II alveolar epithelial cells (A549) with bacillus Calmette –Guérin

Conclusion WPC exposure increased epithelial cells’ permeability and death and enhanced their capacity for macropinocytosis. Our in vitro data suggest possible harmful effects of WPC on the ability of lung epithelial cells to phagocytose mycobacteria. Further studies will be conducted to understand the mechanism of action of WPC.
Source: International Journal of Mycobacteriology - Category: Infectious Diseases Source Type: research