Tmod-20. establishment of a brain tumor model with dysfunctional tumor immunity in mice as a platform for immunotherapeutic evaluation

In conclusion, this novel mouse model may be useful to screen for novel immune checkpoint inhibitors and combination regimes in the setting of a single dysfunctional CD8 T cell response.

Source: Neuro-Oncology - November 6, 2016 Category: Cancer & Oncology Authors: Nakashima, H., Alayo, Q., Penaloza, P., Barouch, D., Chiocca, E. A. Tags: TUMOR MODELS Source Type: research