Tmod-19. properties of cognitive development of children with cerebellar tumor

The aim of the study was to estimate the influence of brain tumor and tumor’s localization on children’s cognitive development. Two groups of children participated in research: 1) children with cerebellar tumor (N=19, aged 10-14); 2) control group of healthy children developing normally (N=30, aged 10-14).METHODS:K-ABC-II (Kaufman Assessment Battery for Children, 2nd Ed.); CANTAB (Cambridge Neuropsychological Test Automated Battery; Cambridge Cognition), selected subtests: SWM (spatial working memory).RESULTS:Analysis of covariance indicated that group of children with cerebellar tumor scored significantly lower in overall intelligence, verbal memory and spatial memory. These data show that the cerebellar tumor has negative impact on intelligence, verbal memory and spatial memory. The study of the group of children with cerebellar tumor did not reveal any relationship between spatial memory and verbal memory scores, and intelligence and spatial memory scores as in control group. Those results may suggest that the spatial memory and verbal memory decline independently of each other and the fact that reduction of spatial memory is not related to the decrease in intelligence. The study was supported by the Russian Foundation for Basic Research, project 15-06-08680. Keywords: memory, verbal memory, spatial memory, cognitive development, brain tumor, cerebellum.
Source: Neuro-Oncology - Category: Cancer & Oncology Authors: Tags: TUMOR MODELS Source Type: research