Tmod-12. a novel patient-derived xenograft model of brain metastasis

CONCLUSION:To the best of our knowledge this is the first report in which the cerebral aqueduct has been targeted for metastatic PDX modeling. Our data indicate that intracranial injection of metastatic cells into the cerebral aqueduct is a reproducible model to study both local growth of metastases and leptomeningeal disease.
Source: Neuro-Oncology - Category: Cancer & Oncology Authors: Tags: TUMOR MODELS Source Type: research