Tmic-18. role of microglia in the early steps of the brain metastatic cascade

In conclusion, our data suggest a step-dependent critical role of BMIC/microglia interactions during the brain metastatic cascade, and also provide a model to investigate the potential of microglia-directed therapies for BM prevention.

Source: Neuro-Oncology - November 6, 2016 Category: Cancer & Oncology Authors: Berghoff, A., Feinauer, M., Solecki, G., Grosch, J., Osswald, M., Gil, B., Wilhelm, D., Raiky, U., Hainfellner, J., Steeg, P., Birner, P., Preusser, M., Wick, W., Winkler, F. Tags: TUMOR MICROENVIRONMENT Source Type: research