Stmc-20. migrating glioma cells express stem cell markers and give rise to new tumors upon xenografting

In conclusion, migrating tumor cells preserve expression of stem cell markers and functional CSC characteristics. Since CSCs are reported to be highly resistant to therapy, these results emphasize that the CSC phenotype should be taken into consideration in future treatment of GBMs.

Source: Neuro-Oncology - November 6, 2016 Category: Cancer & Oncology Authors: Munthe, S., Sorensen, M., Thomassen, M., Burton, M., Kruse, T., Lathia, J., Poulsen, F., Kristensen, B. Tags: STEM CELLS Source Type: research