Rthp-09. progression and pseudoprogression of glioblastoma multiforme in the temozolomide era

CONCLUSIONS:Contrary to published reports, our data do not demonstrate an improvement in survival outcomes for patients with pseudoprogression compared to stable disease or response on first post-radiation imaging. Our data may be limited by patient numbers but importantly, there were no early imaging characteristics, including perfusion imaging, that differentiated pseudoprogression from true progression. These results underscore the need for continued investigations to develop non-invasive techniques to predict pseudoprogression and accurately predict overall survival.

Source: Neuro-Oncology - November 6, 2016 Category: Cancer & Oncology Authors: Rowe, L., Butman, J., Mackey, M., Shih, J., Hawes, M., Cooley Zgela, T., Ning, H., Smart, D., Gilbert, M., Camphausen, K., Krauze, A. Tags: RADIATION THERAPY Source Type: research