RBIO-05. miRNAs THAT CONFER GLIOBLASTOMA RESISTANCE: IS THE COMBINATION MERELY A SUM OF THE PARTS?

CONCLUSION:Through an unbiased, systematic screen designed to identify miR combinations that confer glioblastoma radiation resistance, we uncovered a novel miRNA combination. The effects of the four miRNAs in aggregate was distinct from that seen with each individual siRNAs. The study points to the importance of an integrated study of miRNA combinations relative to the characterization of each individual miRNAs.

Source: Neuro-Oncology - November 6, 2016 Category: Cancer & Oncology Authors: Chen, C., Moskwal, P., Zinn, P., Eun Choi, Y., Shukla, S., Fendler, W., Lu, J., Golub, T., Hjelmeland, A., Chowdhury, D. Tags: RADIOBIOLOGY Source Type: research