RARE-34. DIAGNOSIS AND MOLECULAR CHARACTERIZATION OF CSF-CTCs IN LEPTOMENINGEAL DISEASE (LMDz) FROM UVEAL MELANOMA (UM)

CONCLUSIONS & FUTURE DIRECTIONS:It is possible to make a diagnosis and molecular characterization of LMDz when conventional methods fail using CSF-CTCs. A focused mutational analysis for potential therapeutically relevant targets can be used to guide treatment. The relationship of this selected CSF-CTC marker to the population of CSF-CTCs and therapeutic decisions are being clarified.

Source: Neuro-Oncology - November 6, 2016 Category: Cancer & Oncology Authors: Fedorenko, I., Evernden, B., Kenchappa, R., Sahebjam, S., Ryzhova, E., Puskas, J., Magliocco, A., Etame, A. B., Tran, N. D., Harbour, W., Smalley, K., Forsyth, P. Tags: RARE TUMORS Source Type: research