RARE-18. DETECTION, MOLECULAR PROFILING AND CULTURE OF CSF-CTCs IN LEPTOMENINGEAL DISEASE (LMDz) IN MELANOMA

CONCLUSIONS:These results indicate the potential value of CSF as a biopsy surrogate for assessing genetic makeup of CSF malignancies. Future directions involve the single cell analysis of CSF-CTCs, in vitro drug screens and in vivo LMDz models.

Source: Neuro-Oncology - November 6, 2016 Category: Cancer & Oncology Authors: Evernden, B., Kenchappa, R., Puskas, J., Ryzhova, E., Caceres, G., Fedorenko, I., Tran, N. D., Etame, A. B., Sahebjam, S., Magliocco, A., Smalley, K., Forsyth, P. Tags: RARE TUMORS Source Type: research