Electrophysiology of glioma: a Rho GTPase-activating protein reduces tumor growth and spares neuron structure and function

Conclusions
Our findings demonstrate that CNF1 reduces glioma volume while at the same time maintaining the physiological and structural properties of peritumoral neurons. These data indicate a promising strategy for the development of more effective antiglioma therapies.

Source: Neuro-Oncology - November 8, 2016 Category: Cancer & Oncology Authors: Vannini, E., Olimpico, F., Middei, S., Ammassari-Teule, M., de Graaf, E. L., McDonnell, L., Schmidt, G., Fabbri, A., Fiorentini, C., Baroncelli, L., Costa, M., Caleo, M. Tags: Basic and Translational Investigation Source Type: research