[News & Analysis] Toxicology: 'Humanized' Mouse Detects Deadly Drug Side Effects

An experimental hepatitis B drug that looked safe in animal trials tragically killed five of 15 patients in 1993. Now, researchers have engineered a mouse with a humanized liver that readily detects the drug's toxicity and may serve as a novel toxicity screen for other drugs that have yet to enter human trials. Author: Jon Cohen
Source: Science: This Week - Category: Science Authors: Tags: Toxicology Source Type: research