Taste and Smell Disturbance Resulting From Midodrine

Discussion:
Midodrine is used for symptoms of orthostatic hypotension. Dysgeusia and dysosmia are not common adverse events and are not included in the manufacturer’s labeling. There is only one other published case report of this reaction. Our patient only admitted to slight appetite suppression, but it may be more profound in some. The reaction may be dose related, but there is not enough information to make this conclusion.

Principal conclusions:
Using midodrine may result in dysgeusia and dysosmia. According to this case, both adverse effects may lessen or resolve over time with the use of the medication.

Source: Journal of Pharmacy Practice - November 6, 2016 Category: Drugs & Pharmacology Authors: Horger, S., Kandrac, S., Longyhore, D. S. Tags: Adverse Drug Events Source Type: research