Regulation of Carbohydrate Metabolism, Lipid Metabolism, and Protein Metabolism by AMPK.

Regulation of Carbohydrate Metabolism, Lipid Metabolism, and Protein Metabolism by AMPK.
EXS. 2016;107:23-43
Authors: Angin Y, Beauloye C, Horman S, Bertrand L
Abstract
This chapter summarizes AMPK function in the regulation of substrate and energy metabolism with the main emphasis on carbohydrate and lipid metabolism, protein turnover, mitochondrial biogenesis, and whole-body energy homeostasis. AMPK acts as whole-body energy sensor and integrates different signaling pathway to meet both cellular and body energy requirements while inhibiting energy-consuming processes but also activating energy-producing ones. AMPK mainly promotes glucose and fatty acid catabolism, whereas it prevents protein, glycogen, and fatty acid synthesis.
PMID: 27812975 [PubMed - in process]

Source: EXS - November 6, 2016 Category: Research Tags: EXS Source Type: research