Computationally Efficient Analysis of Particle Transport and Deposition in a Human Whole-Lung-Airway Model. Part II: Dry Powder Inhaler Application

Pulmonary drug delivery is becoming a favored route for administering drugs to treat both lung and systemic diseases. Examples of lung diseases include asthma, cystic fibrosis and chronic obstructive pulmonary disease (COPD) as well as respiratory distress syndrome (ARDS) and pulmonary fibrosis. Special respiratory drugs are administered to the lungs, using an appropriate inhaler device. Next to the pressurized metered-dose inhaler (pMDI), the dry powder inhaler (DPI) is a frequently used device because of the good drug stability and a minimal need for patient coordination.
Source: Computers in Biology and Medicine - Category: Bioinformatics Authors: Source Type: research