Disruption of beta3 adrenergic receptor increases susceptibility to DIO in mouse

In conclusion, ARβ3 inactivation does not affect BAT thermogenesis but increases susceptibility to diet-induced obesity by dampening WAT lipolytic response to adrenergic stimulation.

Source: Journal of Endocrinology - November 2, 2016 Category: Endocrinology Authors: Preite, N. Z., Nascimento, B. P. P. d., Muller, C. R., Americo, A. L. V., Higa, T. S., Evangelista, F. S., Lancellotti, C. L., Henriques, F. d. S., Batista, M. L., Bianco, A. C., Ribeiro, M. O. Tags: Research Source Type: research