Estimation of Radiation Dosimetry for 68Ga-HBED-CC (PSMA-11) in Patients with Suspected Recurrence of Prostate Cancer

This study was performed to estimate the human radiation dosimetry for [68Ga]Ga-HBED-CC (PSMA-11) (68Ga PSMA-11). Methods: Under an RDRC-approved research protocol, we evaluated the biodistribution and pharmacokinetics of 68Ga PSMA-11 with serial PET imaging following intravenous administration to nine prostate cancer patients in whom clinical [11C]acetate PET/CT exams had been independently performed under Expanded Access IND 118,204. List-mode imaging was performed over the initial 0 –10min post-injection with the pelvis in the field-of-view.

Source: Nuclear Medicine and Biology - November 2, 2016 Category: Nuclear Medicine Authors: Mark A. Green, Jacob A. Eitel, James W. Fletcher, Carla J. Mathias, Mark A. Tann, Thomas Gardner, Michael O. Koch, Wendy Territo, Heather Polson, Gary D. Hutchins Source Type: research