Distinct Differences in Striatal Dysmorphology Between Attention Deficit Hyperactivity Disorder Boys with and without a Comorbid Reading Disability

There is evidence of greater cognitive deficits in attention deficit hyperactivity disorder with a comorbid reading disability (ADHD/+RD) compared to ADHD alone (ADHD/-RD). Additionally, the striatum has been consistently implicated in ADHD. However, the extent of morphological alterations in the striatum of ADHD/+RD is poorly understood, which is the main purpose of this study. Based on structural MRI images, the surface deformation of the caudate and putamen was assessed in 59 boys matching in age and IQ [19 ADHD/-RD, 15 ADHD/+RD and 25 typically developing controls (TDC)].

Source: Psychiatry Research: Neuroimaging - November 2, 2016 Category: Psychiatry Authors: Dhruman D. Goradia, Sherry Vogel, Brianne Mohl, Dalal Khatib, Caroline Zajac-Benitez, Usha Rajan, Arthur Robin, David R. Rosenberg, Jeffrey A. Stanley Source Type: research