Characterization of Heparan Sulfate Proteoglycan-positive Recycling Endosomes Isolated from Glioma Cells

Conclusion: Part of HSPGs in glioma cells is internalized through clathrin-dependent endocytosis and undergo recycling. The development of compounds regulating HSPG-mediated trafficking will likely enable design of effective glioma treatment.

Source: Cancer Genomics and Proteomics - November 1, 2016 Category: Cancer & Oncology Authors: PODYMA-INOUE, K. A., MORIWAKI, T., RAJAPAKSHE, A. R., TERASAWA, K., HARA-YOKOYAMA, M. Tags: Article Source Type: research