Immunoexpression of Epithelial Mesenchymal Transition Proteins E-Cadherin, {beta}-Catenin, and N-Cadherin in Oral Squamous Cell Carcinoma

Conclusion. OSCC tissues had high levels of EMT phenotype as compared with the normal oral mucosa. This phenotype was characterized by reduced E-cadherin and β-catenin expression and overexpression of N-cadherin. Aberrant localization of the studied proteins was a hallmark for depicting EMT.

Source: International Journal of Surgical Pathology - October 31, 2016 Category: Pathology Authors: Angadi, P. V., Patil, P. V., Angadi, V., Mane, D., Shekar, S., Hallikerimath, S., Kale, A. D., Kardesai, S. G. Tags: Original Articles Source Type: research