Aberrant Food Choices after Satiation in Human Orexin-Deficient Narcolepsy Type 1

Conclusions:We show that the manipulation of food-specific satiety has reduced effects on food choices and caloric intake in narcolepsy type 1 patients. These mechanisms may contribute to their obesity, and suggest an important functional role for orexin in human eating behavior.Clinical Trials Registration:Study registered at Netherlands Trial Register. URL:www.trialregister.nl. Trial ID: NTR4508.Citation:van Holst RJ, van der Cruijsen L, van Mierlo P, Lammers GJ, Cools R, Overeem S, Aarts E. Aberrant food choices after satiation in human orexindeficient narcolepsy type 1.SLEEP 2016;39(11):1951–1959.
Source: Sleep - Category: Sleep Medicine Source Type: research