Evaluation of sodium hydroxide –N-acetyl-l-cysteine and 0.7% chlorhexidine decontamination methods for recovering Mycobacterium tuberculosis from contaminated sputum samples: A comparative analysis (The Gambia Experience)

Conclusion The 0.7% chlorhexidine decontamination method is rapid and has less contamination rate in terms of mycobacterial recovery compared with the standard NaOH–NALC method. Therefore, the 0.7% chlorhexidine decontamination method would be an ideal alternative option for decontamination of sputum samples and recovery/isolation of M. tuberculosis in resource-poor countries.
Source: International Journal of Mycobacteriology - Category: Infectious Diseases Source Type: research