IgE – the main player of food allergy

Publication date: Available online 26 October 2016 Source:Drug Discovery Today: Disease Models Author(s): Henrike C.H. Broekman, Thomas Eiwegger, Julia Upton, Katrine L. Bøgh Food allergy is a growing problem worldwide, presently affecting 2–4% of adults and 5–8% of young children. IgE is a key player in food allergy. Consequently huge efforts have been made to develop tests to detect either the presence of IgE molecules, their allergen binding sites or their functionality, in order to provide information regarding the patient's food allergy. The ultimate goal is to develop tools that are capable of discriminating between asymptomatic sensitization and a clinically relevant food allergy, and between different allergic phenotypes in an accurate and trustworthy manner. This may generate better diagnostic, prognostic and therapeutic monitoring tools for the future.
Source: Drug Discovery Today: Disease Models - Category: Drugs & Pharmacology Source Type: research