Intra-amniotic Ureaplasma parvum-Induced Maternal and Fetal Inflammation and Immune Responses in Rhesus Macaques

Conclusions. U. parvum colonized the amniotic fluid and caused uterine inflammation, but without overt chorioamnionitis. It caused mild fetal lung inflammation but had a more profound effect on the fetal immune system, decreasing Tregs and polarizing them toward a T-helper 1 phenotype.

Source: The Journal of Infectious Diseases - October 27, 2016 Category: Infectious Diseases Authors: Senthamaraikannan, P., Presicce, P., Rueda, C. M., Maneenil, G., Schmidt, A. F., Miller, L. A., Waites, K. B., Jobe, A. H., Kallapur, S. G., Chougnet, C. A. Tags: PATHOGENESIS AND HOST RESPONSE Source Type: research