Genomic Epidemiology of Gonococcal Resistance to Extended-Spectrum Cephalosporins, Macrolides, and Fluoroquinolones in the United States, 2000-2013

Conclusions. Quinolone-resistant N. gonorrhoeae and reduced cefixime susceptibility appear amenable to development of sequence-based diagnostic tests, whereas the undefined mechanisms of resistance to ceftriaxone and azithromycin underscore the importance of phenotypic surveillance. The identification of multidrug-resistant isolates highlights the need for additional measures to respond to the threat of untreatable gonorrhea.

Source: The Journal of Infectious Diseases - October 27, 2016 Category: Infectious Diseases Authors: Grad, Y. H., Harris, S. R., Kirkcaldy, R. D., Green, A. G., Marks, D. S., Bentley, S. D., Trees, D., Lipsitch, M. Tags: BACTERIA Source Type: research