Seasonal Influenza Vaccination of Children Induces Humoral and Cell-Mediated Immunity Beyond the Current Season: Cross-reactivity With Past and Future Strains

Conclusions. Seasonal influenza viruses continuously drift, which allows them to circumvent protective immunity, but conserved epitopes provide immunological cross-reactivity in children through either vaccination directly or through prime/boost in the prior influenza season.

Source: The Journal of Infectious Diseases - October 27, 2016 Category: Infectious Diseases Authors: Reber, A. J., Kim, J. H., Coleman, L. A., Spencer, S. M., Chung, J. R., Chen, J., Gargiullo, P., Sundaram, M. E., Belongia, E. A., Shay, D. K., Katz, J. M., Sambhara, S. Tags: VIRUSES Source Type: research