The upregulation of annexin A2 after spinal cord injury in rats may have implication for astrocyte proliferation

Annexin A2 (ANXA2), is a member of the annexin family of proteins that exhibit Ca2+-dependent binding to phospholipids. One attractive biological function of ANXA2 is participating in DNA synthesis and cell proliferation. Previous studies have shown that ANXA2 play a role in the development of the central nervous system. However, the biological function of ANXA2 after spinal cord injury (SCI) is still with limited acquaintance. In the present study, we performed a SCI model in adult rats and investigated the dynamic changes of ANXA2 expression in the spinal cord.

Source: Neuropeptides - October 26, 2016 Category: Neuroscience Authors: Jiajia Chen, Zhiming Cui, Saishuai Yang, Chunshuai Wu, Weidong Li, Guofeng Bao, Guanhua Xu, Yuyu Sun, Lingling Wang, Jinlong Zhang Source Type: research