Suppression of TNF- α and free radicals reduces systematic inflammatory and metabolic disorders: radioprotective effects of ginseng oligopeptides on intestinal barrier function and antioxidant defense

This study was aimed to investigate the effects of ginseng (Panax ginseng C. A. Mey.) oligopeptides (GOP) on irradiation-induced intestinal injury and antioxidant defense in mice. BALB/c mice (8 weeks old) were randomly divided into six groups: vehicle control, irradiation control (IR), IR+Whey protein (0.30 g/kg BW), IR+GOP 0.15 g/kg BW, IR+GOP 0.30 g/kg BW, and IR+GOP 0.60 g/kg BW. Post-irradiation 30-day-survival trial, white blood cells count and bone marrow hematopoietic system damage were performed to identify the injury degree induced by irradiation.

Source: The Journal of Nutritional Biochemistry - October 25, 2016 Category: Biochemistry Authors: Li-Xia He, Jun-Bo Wang, Bin Sun, Jian Zhao, Lin Li, Teng Xu, Hui Li, Jing-Qin Sun, Jinwei Ren, Rui Liu, Qi-He Chen, Zhao-Feng Zhang, Yong Li Source Type: research