Circulating histones for predicting prognosis after cardiac surgery: a prospective study

CONCLUSIONS
Circulating histones reached peak levels faster than NT-proBNP, PCT and CRP. Furthermore, peak histone levels correlated with biomarkers and postoperative clinical outcomes. Circulating histones may be used as a prognostic indicator for patients after cardiac surgery with CPB.

CLINICAL TRIALS
ClinicalTrials.gov (ID: NCT02325765).

Source: Interactive CardioVascular and Thoracic Surgery - October 25, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Gao, H., Zhang, N., Lu, F., Yu, X., Zhu, L., Mo, X., Wang, W. Tags: Mechanical Circulatory Assistance Congenital Source Type: research