Genome wide association study identifies two loci associated with cadmium in erythrocytes among never-smokers

Conclusion: This genome-wide study of never smokers from the general population identified two independent regions related to erythrocyte cadmium. The strongest locus covers the XKR9 and LACTB2 genes, which both could have related functions in cadmium absorption and metabolism. Replication studies are needed to confirm the findings and mechanisms should be further investigated.

Source: Human Molecular Genetics - October 23, 2016 Category: Genetics & Stem Cells Authors: Borne, Y., Söderholm, M., Barregard, L., Fagerberg, B., Persson, M., Melander, O., Thevenod, F., Hedblad, B., Engström, G. Tags: ASSOCIATION STUDIES ARTICLES Source Type: research