Novel Gastroretentive Controlled Release Formulations for Once-Daily Administration: Assessment of Clinical Feasibility and Formulation Concept for Raltegravir

Conclusions:
The findings from these studies offer valuable insights into modifying the absorption of candidate drugs with limiting colonic permeability and solubility characteristics and the interplay between meal, dose timing, and GR formulation performance.

Source: Therapeutic Innovation and Regulatory Science - October 23, 2016 Category: Drugs & Pharmacology Authors: Krishna, R., Rizk, M. L., Larson, P. J., Schulz, V., Friedman, E., Gupta, P., Kesisoglou, F., Connor, A., McDermott, J., Smith, R., Evans, P. Tags: Product Development and Innovation Source Type: research