Reply Diagnostic Ultrasound Impulses Improve Microvascular Flow in Patients With STEMI Receiving Intravenous Microbubbles

We thank Dr. D ’Amario and colleagues for their interest in our recently published study and their intriguing preliminary findings with transthoracic diagnostic high mechanical index (HMI) ultrasound in the RIGENERA 2.0 (Recupero Dall'Infarto Miocardico Con G-CSF E Nuovi Esempi di Rigenerazione Avanzata, [NCT025 02747]).(1). In this trial, the authors have discovered that intermittent HMI ultrasound impulses with a standard diagnostic system (i.e., 33, Philips Healthcare, Bothel, Washington) during a lipid encapsulated microbubble infusion before granulocyte colony –stimulating factor (GCSF) injection resulted in greater improvements in left ventricular ejection fraction following acute anterior myocardial infarction. They have designed a trial in which they will now randomize patients with large anterior wall myocardial infarctions who have left ventricular ejection fraction 

Source: Journal of the American College of Cardiology - October 25, 2016 Category: Cardiology Source Type: research