The interplay between cell signalling and the mevalonate pathway in cancer
Nature Reviews Cancer 16, 718 (2016).
doi:10.1038/nrc.2016.76
Authors: Peter J. Mullen, Rosemary Yu, Joseph Longo, Michael C. Archer & Linda Z. Penn
The mevalonate (MVA) pathway is an essential metabolic pathway that uses acetyl-CoA to produce sterols and isoprenoids that are integral to tumour growth and progression. In recent years, many oncogenic signalling pathways have been shown to increase the activity and/or the expression of MVA pathway
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Peter J. Mullen Rosemary Yu Joseph Longo Michael C. Archer Linda Z. Penn Tags: Review Source Type: research
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