The metabolic fate of acetate in cancer

Nature Reviews Cancer 16, 708 (2016). doi:10.1038/nrc.2016.87 Authors: Zachary T. Schug, Johan Vande Voorde & Eyal Gottlieb Recent high-profile reports have reignited an interest in acetate metabolism in cancer. Acetyl-CoA synthetases that catalyse the conversion of acetate to acetyl-CoA have now been implicated in the growth of hepatocellular carcinoma, glioblastoma, breast cancer and prostate cancer. In this Review, we discuss how acetate
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Review Source Type: research