Altered metabolite levels in cancer: implications for tumour biology and cancer therapy

Nature Reviews Cancer 16, 680 (2016). doi:10.1038/nrc.2016.85 Authors: Lucas B. Sullivan, Dan Y. Gui & Matthew G. Vander Heiden Altered cell metabolism is a characteristic feature of many cancers. Aside from well-described changes in nutrient consumption and waste excretion, altered cancer cell metabolism also results in changes to intracellular metabolite concentrations. Increased levels of metabolites that result directly from genetic mutations and cancer-associated modifications
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Review Source Type: research