Immunology: Skin inflammation predisposes to cancer
Nature Reviews Cancer 16, 678 (2016).
doi:10.1038/nrc.2016.120
Author: Gemma K. Alderton
Inflammasome complexes are important effectors of innate immune responses, and chronic inflammation in the gut has been linked to tumorigenesis. Zhong et al. have found germline gain-of-function mutations in the gene encoding the inflammasome receptor, NLRP1. These mutations cause two skin disorders that are
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Gemma K. Alderton Tags: Research Highlight Source Type: research
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