Immunology: Skin inflammation predisposes to cancer

Nature Reviews Cancer 16, 678 (2016). doi:10.1038/nrc.2016.120 Author: Gemma K. Alderton Inflammasome complexes are important effectors of innate immune responses, and chronic inflammation in the gut has been linked to tumorigenesis. Zhong et al. have found germline gain-of-function mutations in the gene encoding the inflammasome receptor, NLRP1. These mutations cause two skin disorders that are
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Research Highlight Source Type: research