Tumour metabolism: Targeting proline metabolism?

Nature Reviews Cancer 16, 678 (2016). doi:10.1038/nrc.2016.119 Author: Gemma K. Alderton Proline is a non-essential amino acid and Sahu et al. show that some cancer cells are dependent on proline for clonogenicity and tumorigenic potential. These authors profiled a panel of cancer cell lines and found that proline consumption and the expression of enzymes involved
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Research Highlight Source Type: research