Profile of autonomic dysfunctions in patients with primary brain tumor and possible autoimmunity

Cerebral lesion due to different neurological conditions, e.g. stroke, head injury, inflammation, etc., with high intracranial pressure, could be complicated by autonomic dysfunction. Autonomic dysregulation was reported in the literature as a sympathetic hyperactivity, in some cases, mostly after brain injury, as a severe “paroxysmal sympathetic storm”. Dysfunction of autonomic centers in diencephalon, insular cortex, or even anterior cingulated, loss of the cortical or subcortical control, activation or dysinhibition of sympathoexcitatory regions are possible in the pathogenesis of dysautonomia [1–5].

Source: Clinical Neurology and Neurosurgery - October 21, 2016 Category: Neurosurgery Authors: Magdalena Koszewicz, Slawomir Michalak, Malgorzata Bilinska, Slawomir Budrewicz, Mikolaj Zaborowski, Krzysztof Slotwinski, Ryszard Podemski, Maria Ejma Source Type: research