Metabolic Outcomes of Bergamot Polyphenolic Fraction Administration in Patients Treated with Second-Generation Antipsychotics: a Pilot Study

Second-generation antipsychotics (SGAs) are notoriously associated with a marked increase in body weight and with a wide range of metabolic adverse effects, and their chronic use is related with an increased risk for the development of metabolic syndrome (MS). Different adjunctive treatments have been proposed to reduce SGAs-induced weight gain and/or metabolic abnormalities with inconsistent or too limited evidence to support their regular clinical use, thus suggesting the need to find new possible treatments.

Source: The Journal of Nutritional Biochemistry - October 21, 2016 Category: Biochemistry Authors: Antonio Bruno, Gianluca Pandolfo, Manuela Crucitti, Antonino Maisano, Rocco A. Zoccali, Maria Rosaria Anna Muscatello Source Type: research